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Current Opinion in Otolaryngology & Head and Neck Surgery - Current Table Of Contents

Editorial introductions.
Page: viDOI: 10.1097/MOO.0b013e32831fb47b
Editorial comment.
Page: 497DOI: 10.1097/MOO.0b013e328317797eAuthors: Belafsky, Peter C
The diagnosis and management of globus: a perspective from Japan.
Page: 498DOI: 10.1097/MOO.0b013e328313bb69Authors: Oridate, Nobuhiko a; Nishizawa, Noriko a,b; Fukuda, Satoshi a

Archives of Otolaryngology current issue

ABOUT THE COVER: Booth Lake, Indian Peaks Wilderness Area, Colorado
Mon, 15 Dec 2008 00:00:00 -0000

ABOUT THIS JOURNAL: About This Journal
Mon, 15 Dec 2008 00:00:00 -0000

ANNUAL REVIEWERS LIST: Reviewers Who Completed a Review During 2008
Levine, P. A. Mon, 15 Dec 2008 00:00:00 -0000

ORIGINAL ARTICLE: Snoring, Daytime Sleepiness, and Nasal Obstruction With or Without Allergic Rhinitis
Hiraki, N., Suzuki, H., Udaka, T., Shiomori, T. Mon, 15 Dec 2008 00:00:00 -0000
Objective  To investigate the relationships among nasal obstruction (NO), snoring, and excessive daytime sleepiness (EDS) in working people with or without allergic rhinitis (AR). Design  Prospective study using questionnaires. Setting  An industrial company in Japan. Participants  We asked 1878 daytime workers to complete questionnaires; data from 1459 respondents were analyzed. Participants were divided into 3 groups: those with NO plus AR, those with NO without AR, and those with AR without NO. Individuals without NO or AR served as controls. Main Outcome Measures  Allergic rhinitis and daytime sleepiness were evaluated using the European Community Respiratory Health Survey questionnaire and the Epworth Sleepiness Scale, respectively. Results  The percentage of snorers, the Epworth Sleepiness Scale score, and the percentage of participants with EDS were higher in the NO-AR and NO groups but were not significantly different in the AR group compared with the control group. These variables did not differ between the NO-AR and NO groups. Patients in the NO-AR and NO groups had higher odds of snoring and of having EDS, whereas the odds of snoring or of having EDS were not statistically significant in the AR group compared with the control group (P = .67 and P = .3, respectively). Conclusions  Nasal obstruction is associated with snoring and EDS in individuals with or without AR. Allergic rhinitis without NO is not associated with sleep-disordered breathing or EDS.
ORIGINAL ARTICLE: Production of Allogenic Cartilage in a Tube Lined With Epithelium and a Novel Scaffold
Cheng, Y., Huang, J., Li, Z., Zhou, M., Wang, T., Jiang, M., Wang, Q.-p. Mon, 15 Dec 2008 00:00:00 -0000
Objective  To study the feasibility of engineering cartilage tissue in a tube lined with epithelium and implanting allogenic chondrocytes in a novel scaffold that is made of chitosan nonwoven cloth coated with poly(dl-lactide-co-glycolide). Design  Laboratory research. Subjects  Allogenic chondrocytes were obtained from the auricles of 1-month-old New Zealand white rabbits. After the cells were cultured in vitro for 3 or 4 passages, they were implanted in the scaffolds to form composite grafts and then transplanted into the rabbits. After 6, 12, and 18 weeks, the general histologic characteristics were investigated. Results  The cobweb-like matrix was observed approximately 1 week after the chondrocytes had been implanted in the scaffolds. At 6 weeks, the matrix was secreted, and there were immature chondrocytes in the grafts. At 12 weeks, the allogenic cartilage in the tube lined with epithelium had been created. Chondrocytes were almost mature and the lacunae had formed. At 18 weeks, the neocartilage was similar to native cartilage. Conclusion  It is feasible to produce allogenic cartilage in a tube lined with epithelium by implanting allogenic chondrocytes into a novel scaffold made of chitosan nonwoven cloth coated with poly(dl-lactide-co-glycolide).
ORIGINAL ARTICLE: Window Anterior Commissure Relaxation Laryngoplasty in the Management of High-Pitched Voice Disorders
Kocak, I., Dogan, M., Tadihan, E., Alkan Cakir, Z., Bengisu, S., Akpinar, M. Mon, 15 Dec 2008 00:00:00 -0000
Objective  To present the success rate of a less invasive modification of Isshiki type III anterior commissure relaxation laryngoplasty technique in patients with high-pitched voice disorders. Design  Prospective case series. Setting  KBB Major Private Clinic of Istanbul Surgery Hospital and the University of Yeditepe Hospital. Patients  Twenty-one adult patients who believed that their high-pitched voices conflicted with their body image and/or gender identity. Intervention  Type III thyroplasty for pitch alteration. Main Outcome Measures  Comparison of preoperative and postoperative (>6 months) fundamental frequency levels, diplophonia, perception of body image and pitch, and subjective ratings of comfort during vocalization. Results  The patients were mostly male (mean age, 30.5 years). The most frequent cause of high-pitched voice was sulcus vocalis (n = 14), followed by constitutional causes (n = 5), mutational falsetto (n = 1), and severe glottic scarring secondary to childhood diphtheria (n = 1). After surgery, the fundamental frequency dropped significantly from a mean of 213.81 Hz to 149.86 Hz (P < .001), equaling a mean postoperative semitone drop of 6.23. Misperception leading to an abnormal body image was reduced by 86%. Fourteen patients who originally had feelings of tension and fatigue during phonation and vocalization gained comfort postoperatively. Diplophonia with subharmonic signals observed in 11 cases preoperatively was reduced or disappeared in 6 cases. No complications or failures were observed during the follow-up period. Conclusion  Window anterior commissure relaxation laryngoplasty is an efficient, easy, less invasive, and safe procedure in the surgical management of organic and functional high-pitched voice disorders.

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